RT Book, Section A1 Padley, Anthony P. SR Print(0) ID 1208529632 T1 A-A GRADIENT T2 Westmead Anaesthetic Manual, 5th Edition YR 2024 FD 2024 PB McGraw Hill PP New York, NY SN 9781760427283 LK accessworldmed.mhmedical.com/content.aspx?aid=1208529632 RD 2024/12/09 AB The A-a gradient is the difference between the partial pressure of oxygen in the alveolus (PAO2) and the partial pressure of oxygen in the arterial blood (PaO2). PAO2 is the ‘ideal’ alveolar PO2. The A-a gradient is helpful in diagnosing the cause of hypoxia. See Hypoxia/hypoxaemia.